Duodenal Organoids From Metabolic Dysfunction-Associated Steatohepatitis Patients Exhibit Absorptive and Barrier Alterations
Background and Aims: Metabolic dysfunction-associated steatohepatitis (MASH) is a progressive liver disease that can lead to fibrosis, cirrhosis, and hepatocellular carcinoma.Though MASH is closely tied to metabolic risk factors, the underlying pathogenic mechanisms remain scarcely understood.Recent research has emphasized the importance of the Ori